GPCR function and physiology

Our team seeks to investigate selective ligands of GPCRs in order to uncover cell signaling and physiology, discover GPCRs-based innovative small molecule therapeutics, and build new chemogenetic platform technology using synthetic biology.

Home: Welcome

RESEARCH

We employ cell-based assay development, high-throughput screening, ultralarge docking and structural biology to better understand how ligand maintain distinct receptor conformations that induce its physiological effects.

We also use structure-based drug design to computationally screen vast chemical libraries against our structures to discover and create new compounds that may be used to produce improved treatments.

Home: Research

Integrative research on GPCRs and their specific ligands to examine cell signaling and physiology

Orphan GPCR probe creation for elucidating unique physiological mechanism

Synthetic biology-based chemogenetic platform technology development for in vivo GPCR function investigation

CONTACT US

kang.hyejin@yonsei.ac.kr

Home: Contact